at The Jackson Laboratory in Bar Harbor, Maine, United States
Associate Research Scientist | Mitochondria in Inflammation and Disease
Bar Harbor, ME
The West lab is relocating to The Jackson Laboratory and is seeking an independent, highly motivated PhD-level scientist to lead a collaborative research program to investigate how mitochondrial dysfunction potentiates disease-associated inflammatory responses in primary mitochondrial disorders and cardiomyopathy. The overall goals of our laboratory are to delineate how mitochondria function as central regulators of innate immune and inflammatory responses and to investigate how mitochondria-immune crosstalk contributes to disease and aging. Our laboratory pursues a multidisciplinary approach by integrating cell biology, immunology, and physiology using cutting-edge techniques including engineered mouse models, single-cell multi-omics, super-resolution imaging, and CRISPR-based cellular tools ().
The ideal candidate should have a strong training background in cell and molecular biology and/or immunology, wet lab and computational experience, and prior expertise using in vivo mouse models. Through leading this program, this talented individual would have access to a world-class consortium of experts in aging and associated diseases as well as cancer biology through The Jackson Laboratory's NCI-Designated JAX Cancer Center.
Following a training period, perform experiments and obtain data with minimal guidance; supervise junior staff to do the same
Develop and optimize protocols
Write manuscripts and grants, will be encouraged to obtain independent funding
Execute and analyze independent research project(s) using efficient, flexible, and self-motivated work ethic
Actively read scientific literature and develop new ideas for project direction(s)
Organize and lead collaborative group projects internally and externally
Contribute to ongoing projects within the lab by being an active team player
Mentor and supervise incoming trainees and lab members as needed
Prepare and give presentations on project(s) at research conferences and symposiums
Ph.D. in cell biology, molecular biology, genetics, or related field of study
3+ years of post-doctoral training
Strong publication record in peer-reviewed journals
Ability to integrate and apply feedback in a professional manner
Exceptional organization and project management skills
Demonstrated resourcefulness in finding appropriate solutions to problems and initiative in presenting alternatives and implementing solutions
Experience using wet lab techniques, animal models and computational tools. Particularly desirable are experience in single cell transcriptomics, flow cytometry, histology and confocal microscopy, genetically diverse mouse models, genetic and genomic data analyses
Excellent writing and communication skills, able to work independently and effectively with other members in a productive team
**Please submit your current CV and 1-page (maximum) statement of Research Interests and Career Goals at time of application. **
We are a diverse and inclusive research group, aspiring to produce top science and scientists through attentive and progressive men
The Jackson Laboratory (JAX) is an independent, nonprofit biomedical research institution with more than 2,400 employees. Headquartered in Bar Harbor, Maine, it has a National Cancer Institute-designated Cancer Center in Augusta, Maine, a genomic medicine institute in Farmington, Connecticut, and facilities in Ellsworth, Maine, Sacramento, California, and Shanghai, China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health.
JAX employees work in a collaborative, value-driven, and team-based environment where the focus is on advancing science and improving patients' lives. Researchers apply genetics to increase the understanding of human disease and advance treatments and cures for cancer, neurological and immune disorders, diabetes, aging, and heart disease. JAX was voted among the top 15 "Best Places to Work in Academia" in the United States in a poll conducted by The Scientist magazine!
The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability or protected veteran status.