at The Jackson Laboratory in Bar Harbor, Maine, United States
Job Description
The Manager of Clinical Genomic Data Analytics and Reporting is expected to participate in the clinical production, validation, development efforts of the JAX clinical genomics laboratory. In this capacity, the manager provides day-to-day oversight of the analytics and reporting team in their clinical reporting efforts, while coordinating with the wet lab, QA, IT teams and Clinical Laboratory Director to ensure the laboratory meets all reporting and compliance benchmarks. In addition, is expected to take a lead role in coordinating with the R&D team for the design and development of new assays that are to be brought into the clinical laboratory. Further, the manager is expected to participate in validation efforts as additional assays are on boarded and guarantee that all assay performance and documentation meets our quality standards. In addition to these main responsibilities, ancillary activities including aiding in research efforts of both internal and external collaborators to help support the mission of The Jackson Laboratory as a whole. These efforts include providing insight and expertise on various subject matters, working on scoping and feasibility planning for collaborations between the clinical laboratory and researchers, as well as providing routine analysis and reporting of research data generated within the clinical laboratory.
Lastly, the manager is expected to serve as representative of the clinical laboratory in such arenas as scientific publications, genomic tumor boards or scientific conferences.
Degree Requirements:
* A Ph.D. degree in genetics, genomics, translational research, molecular biology, or similar biological discipline
Certifications:
ASCP (MB) certification preferred or commitment to get certified within a year of onboarding.
Experience Requirements:
5 -7 years
Key Responsibilities and Essential Functions
General Supervisor (CLIA) - Analysis & Reporting -
Supervise the day-to-day operations of the clinical genomic data analysis and reporting group. Responsible for assigning production and research work to the scientists of the Analysis & Reporting team as appropriate.
Responsible for training members of the Analysis & Reporting team for clinical testing.
Prioritizes clinical cases along with research projects to ensure all results are delivered within expected clinical turnaround times and/or agreed upon project timelines.
Directly oversee efficiency, documentation, SOP's, and general lab activity of the clinical genomics analytics and reporting processes.
Develop/implement process control and QA/QC measures and ensure personnel follow prescribed SOP's and practices. Contribute to the preparation of plans for the validation of new assays and verification of assay performance.
Contribute to the development and maintenance of all related project metrics, including those needed to monitor contractual obligations.
Collaborates and builds successful working relationships with team leads from other JAX laboratories to maximize use of resources, fulfill the missions of JAX and exceed the goals of the clinical genomics lab, acting as the focal point for both internal and external communications as to analysis and reporting development tasks.
This includes providing updates to both the user community and necessary staff. This person also monitors projects, determines potential problems and guides them to successful completion.
Clinical Assay Development -
Operate as the technical lead for the clinical laboratory as new assays are developed by the R&D team.
Lead the construction of development plans to ensure developed assays are suitable for clinical validation after handoff from R&D to production.
Coordinate with the R&D, Wet Lab, Bioinformatics, and Quality teams as appropriate.
In collaboration with the Clinical Bioinformatics team, lead the design and implementation of dry lab processes for new assays in development.
Collaborate with R&D technologists to provide feedback and troubleshooting for R&D technologists as new tests are developed for the clinical laboratory.
Clinical Testing -
Perform clinical assay interpretation and reporting as needed, including data from next generation sequencing panels, quantitative PCR, fragment length analysis, and high-resolution melt analysis tests.
Additional Responsibilities -
Meet with internal and external collaborators to discuss scoping and feasibility.
Serve as laboratory's subject expert when applicable.
Prepare and present data for scientific publications and conferences.
Serve as subject matter expert at genomic tumor boards.
Knowledge, Skills, and Abilities:
A Ph.D. degree in genetics, genomics, translational research, molecular biology or similar biological discipline with 5 years of work... For full info follow application link.
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability or protected veteran status.
