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Bioinformatics Analyst Student Intern, NEU

at The Jackson Laboratory in Bar Harbor, Maine, United States

Job Description

This position is available to Northeastern University students who are currently enrolled and eligible for Co-op January - June 2023.
Summary
The Jackson Laboratory (JAX) is seeking an intern to join the Computational Sciences (CS) department. The successful candidate will work on pipeline development, analyzing Next-Generation Sequencing (NGS) data. The intern will have an opportunity to collaborate with the experts in cancer and immunology fields and to be included in the publications as a co-author.

There are two project options available for this position. Both projects will provide the opportunity to work using cutting-edge technologies with an application to cancer or SARS-CoV2 research.

Project 1:
Workflow development and/or evaluation and the analysis of single-cell RNA-seq (scRNA-seq) datasets from human airway epithelial cells infected with SARS-CoV2

Project 2:
Workflow development and/or evaluation and the analysis of triple negative breast cancer (TNBC) in PDX models using short- and long-read sequencing

Responsibilities
Project 1:
Evaluation of available tools for scRNA-seq analysis
Integration of scRNA-seq and bulk RNA-seq datasets
Workflow development and documentation
Statistical analysis, visualizations

Project 2:
Analysis of short- and long-read RNA-seq datasets
Evaluation and refinement of available integration pipelines
Workflow development and documentation
Statistical analysis, visualizations

Desired Qualifications
Desire to learn new skills and interest in the medical biology and/or computational biology fields
Ability to work independently, communicate well, ask questions, be organized, and make documentation of all written code for the project
Familiarity with UNIX, bash languages, and R

Preferred(not required):
Experience in NGS data analysis
Experience with Git, Bitbucket, Docker, and Singularity
Knowledge of cancer/immunology (depending on a project)
Cover letter indicating project interest

About JAX:
The Jackson Laboratory (JAX) is an independent, nonprofit biomedical research institution with more than 2,400 employees. Headquartered in Bar Harbor, Maine, it has a National Cancer Institute-designated Cancer Center in Augusta, Maine, a genomic medicine institute in Farmington, Connecticut, and facilities in Ellsworth, Maine, Sacramento, California, and Shanghai, China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health.
JAX employees work in a collaborative, value-driven, and team-based environment where the focus is on advancing science and improving patients' lives. Researchers apply genetics to increase the understanding of human disease and advance treatments and cures for cancer, neurological and immune disorders, diabetes, aging, and heart disease. JAX was voted among the top 15 "Best Places to Work in Academia" in the United States in a poll conducted by The Scientist magazine!

EEO Statement:
The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability or protected veteran status.

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Job Posting: 826435

Posted On: Sep 30, 2022

Updated On: Nov 05, 2022