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Bar Harbor, ME 04609
Scientist, PostDoctoral Associate, Professor/Faculty
This is an exciting opportunity to join JAX as a Study Director for in vivo pharmacology services! The in vivo group assists industry and academic researchers in their drug development program, by conducting efficacy studies on carefully baselined and validated models for a variety of neurobiology indications including neurodegeneration, motor neuron diseases, and mitochondrial diseases. Study Directors have ultimate accountability for ensuring studies are executed to the specifications of the client, following gold-standard scientific procedures, meeting or exceeding client expectations without deviation and on a specific budget. They are required to check results for inaccuracies, technical or model-related performance issues, and interpret datasets for the clients. The successfull applicant for this specific role will have a proven expertise in modelling neurological diseases in mouse models, developing and using standardized, recognized behavioral protocols to phenotype these models, and performing histological examinations. The position is responsible for mentoring Project Manager(s), Senior Project Manager(s), and a team of technicians tasked with executing scientific studies on behalf of external or internal customers in a collaborative in vivo laboratory environment. In addition, the Study Director will ensure accuracy in quoting, scheduling and invoicing of the studies. She/He will also be responsible for depositing normative data from mouse models into the public domain via the Mouse Phenome Database, publications and conference presentations, to further the mission of the Jackson Laboratory.
Provide scientific guidance and support to clients in the areas of neurodegeneration, motor neuron diseases, and mitochondrial diseases (for example SMA, Friedreich’s Ataxia, and state-of-the-art phenotyping assays, meeting or exceeding their expectations for quality of service and execution of science.
- Project management of in vivo studies, alone or with the support of Project Managers
- Provide leadership to staff within the in vivo group ensuring they have adequate training and mentoring to support the in vivo services and drive for scientific quality and operational efficiency.
- Ensure staff understand and are compliant with all policies, procedures and practices established by the organization thus ensuring the most efficient operation of the laboratory to provide the highest quality scientific service while meeting organizational compliance, operations and financial targets.
- Lead, in consultation with colleagues, the establishment of agreed standards for the most frequently run studies and ensure these standards are followed in the execution of contracted studies. Collect and ensure that baseline model performance data (such as disease induction rate, disease progression timeline, phenotypes) are compiled, submitted to the Associate Director of Neurobiology and Business Unit Manager, and shared with colleagues.
- Application for grants where possible for funding the research and development of new study platforms; writing of manuscripts when applicable.
- Ph.D. in a life science is required.
- Minimum of 4 years post-doctoral experience in a contract research laboratory, pharmaceutical or biotechnology industries, or equivalent experience.
- Experience with in vivo study design and animal research (preferably rodents) with a proven expertise in genetically-modified models for neurological disease.
- Documented ability to develop and standardize phenotyping and histological assays relevant to neurological diseases.
- Excellent management/supervisory skills and proven experience with mentoring direct reports.
- Documented ability to develop and lead technical teams.
- Strong leadership skills including a demonstrated ability to build key relationships, influence and motivate others.
- Demonstrated success in making important decisions, often under some pressure and tight time deadlines, which carry large financial consequences.
- Must have excellent human relation, communication and listening, negotiation and relationship skills
- Excellent oral and written communication skills.
The Jackson Laboratory (JAX) is an independent, nonprofit biomedical research institution with more than 2,300 employees. Headquartered in Bar Harbor, Maine, it has a National Cancer Institute-designated Cancer Center, a genomic medicine institute in Farmington, Conn., and facilities in Ellsworth, Maine, Sacramento, Calif., and Shanghai, China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health.
The Jackson Laboratory’s 43-acre scenic Bar Harbor campus is nestled between the Gulf of Maine and the mountains of Acadia National Park. Some of the best hiking and biking in the world (over 50 square miles of mountains, lakes, views, and dramatic coastline) is accessible from our campus. We are one mile from downtown Bar Harbor, which offers a vibrant downtown district with a plethora of restaurants, shops, museums, and galleries.
JAX employees work in a collaborative, value-driven, and team-based environment where the focus is on advancing science and improving patients’ lives. Researchers apply genetics to increase the understanding of human disease and advance treatments and cures for cancer, neurological and immune disorders, diabetes, aging, and heart disease. JAX was voted among the top 15 “Best Places to Work in Academia” in the United States in a poll conducted by The Scientist magazine!
INTEGRITY – Courage and commitment to do what is right
PEOPLE – Inspiring our people to enhance the health of all
ONE TEAM – Unified by our promise to transform medicine and science
EXCELLENCE – Achieving world-class results
INNOVATION – Leading with discovery and creative solutions
STEWARDSHIP – Caring for and enhancing the resources entrusted to us
What do we have to offer?
JAX offers a dynamic and supportive work environment, competitive salaries, and a comprehensive benefits package, including a medical plan, outstanding retirement plan, generous paid time off, and tuition reimbursement including an MBA program. Our campus offers a fitness center with an award-winning wellness program, an onsite full service cafeteria, and a fully operational primary care facility available to employees and their families.
Most importantly, every position contributes to JAX’s mission of discovering precise genomic solutions for human disease and empowering the global biomedical community in our shared quest to improve human health.
The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.
Learn more about career opportunities at JAX: http://www.jax.org/careers.
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability or protected veteran status.